Issue 35, 2015

Virus-inspired mimics: self-assembly of dendritic lipopeptides into arginine-rich nanovectors for improving gene delivery

Abstract

With inspirations from natural viruses, arginine-containing dendritic lipopeptides were designed for bioinspired fabrication. Self-assembling the defined amphiphilic lipopeptides generated virus-inspired nanovectors with an arginine-rich corona. These nanovectors provided some remarkable benefits for gene delivery, including well-defined nanostructure, high transfection efficiency, serum resistance and low cytotoxicity.

Graphical abstract: Virus-inspired mimics: self-assembly of dendritic lipopeptides into arginine-rich nanovectors for improving gene delivery

Supplementary files

Article information

Article type
Communication
Submitted
16 شعبان 1436
Accepted
11 شوال 1436
First published
12 شوال 1436

J. Mater. Chem. B, 2015,3, 7006-7010

Author version available

Virus-inspired mimics: self-assembly of dendritic lipopeptides into arginine-rich nanovectors for improving gene delivery

X. Xu, Q. Jiang, X. Zhang, Y. Nie, Z. Zhang, Y. Li, G. Cheng and Z. Gu, J. Mater. Chem. B, 2015, 3, 7006 DOI: 10.1039/C5TB01070E

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