Issue 35, 2009
From the journal:

Chemical Communications

Intramolecular cross-coupling of gem-dibromoolefins: a mild approach to 2-bromo benzofused heterocycles†‡

Stephen G. Newman,a   Valentina Aureggi,a   Christopher S. Bryana  and  Mark Lautens*a  

* Corresponding authors

a Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Canada
E-mail: mlautens@chem.utoronto.ca
Fax: +1 416 946 8185
Tel: +1 416 978 6083

Abstract

Highly useful halogenated benzofurans and benzothiophenes are prepared from readily available gem-dibromoolefins using a mild, ligand-free copper catalyzed cross-coupling procedure.

Graphical abstract: Intramolecular cross-coupling of gem-dibromoolefins: a mild approach to 2-bromo benzofused heterocycles

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Article information

DOI
https://doi.org/10.1039/B912093A
Article type
Communication
Submitted
26 جمادى الثانية 1430
Accepted
23 رجب 1430
First published
15 شعبان 1430

Chem. Commun., 2009, 5236-5238

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Intramolecular cross-coupling of gem-dibromoolefins: a mild approach to 2-bromo benzofused heterocycles

S. G. Newman, V. Aureggi, C. S. Bryan and M. Lautens, Chem. Commun., 2009, 5236 DOI: 10.1039/B912093A

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