Issue 11, 2023

Recent advances in the cyclization reactions of pyridinium 1,n-zwitterions (n = 4 and 5): scope and mechanism

Abstract

Nitrogen- and sulfur-containing heterocyclic compounds widely exist in bioactive natural products and drug molecules with unique bioactivity. In the past few decades, great efforts have been devoted to developing convenient and efficient strategies for the synthesis of these compounds. Pyridinium zwitterions with unique reactivity play a significant role in the construction of nitrogen- and sulfur-containing heterocycles. In recent years, pyridinium zwitterions have been extensively used in cyclization reactions for the synthesis of novel heterocyclic compounds. This review summarizes the recent advances in cyclization reactions involving pyridinium 1,n-zwitterions (n = 4 and 5) and highlights the applications of these zwitterions in the efficient construction of heterocycles.

Graphical abstract: Recent advances in the cyclization reactions of pyridinium 1,n-zwitterions (n = 4 and 5): scope and mechanism

Article information

Article type
Review Article
Submitted
23 رجب 1444
Accepted
28 رمضان 1444
First published
29 رمضان 1444

Org. Chem. Front., 2023,10, 2813-2829

Recent advances in the cyclization reactions of pyridinium 1,n-zwitterions (n = 4 and 5): scope and mechanism

J. Huang, L. Zhang and X. Meng, Org. Chem. Front., 2023, 10, 2813 DOI: 10.1039/D3QO00228D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements