Issue 52, 2023

An ambient pressure, direct hydrogenation of ketones

Abstract

We report two bifunctional (pyridyl)carbene-iridium(I) complexes that catalyze ketone and aldehyde hydrogenation at ambient pressure. Aryl, heteroaryl, and alkyl groups are demonstrated, and mechanistic studies reveal an unusual polarization effect in which the rate is dependant of proton, rather than hydride, transfer. This method introduces a convenient, waste-free alternative to traditional borohydride and aluminum hydride reagents.

Graphical abstract: An ambient pressure, direct hydrogenation of ketones

Supplementary files

Article information

Article type
Communication
Submitted
08 شعبان 1444
Accepted
05 ذو القعدة 1444
First published
20 ذو القعدة 1444

Chem. Commun., 2023,59, 8107-8110

Author version available

An ambient pressure, direct hydrogenation of ketones

L. Zhang, Z. Lu, A. R. Rander and T. J. Williams, Chem. Commun., 2023, 59, 8107 DOI: 10.1039/D3CC01014G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements