Background free in vivo29Si MR imaging with hyperpolarized PEGylated silicon nanoparticles

Seung-Hyun Yang; Jiwon Kim; Tae Geol Lee; Mirae Park; Hye Young Son; Chan Gyu Joo; Jeong Hyun Shim; Youngbok Lee; Yong-Min Huh

doi:10.1039/D3AN01395B

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Background free in vivo²⁹Si MR imaging with hyperpolarized PEGylated silicon nanoparticles†

Seung-Hyun Yang,‡^ad Jiwon Kim,‡^b Tae Geol Lee,^c Mirae Park,^a Hye Young Son,^ad Chan Gyu Joo,^e Jeong Hyun Shim,*^c Youngbok Lee

*^bf and Yong-Min Huh*^adg

Author affiliations

* Corresponding authors

^a Department of Radiology, College of Medicine, Yonsei University, Seoul, Republic of Korea
E-mail: YMHUH@yuhs.ac

^b Department of Bionano Technology, Center for Bionano Intelligence Education and Research, Hanyang University, Ansan, Republic of Korea
E-mail: yblee@hanyang.ac.kr

^c Korea Research Institute of Standards and Science, Daejeon, Republic of Korea
E-mail: jhshim@kriss.re.kr

^d YUHS-KRIBB Medical Convergence Research Institute, College of Medicine, Yonsei University, Seoul, Republic of Korea

^e Severance Biomedical Science Institute, College of Medicine, Yonsei University, Seoul, Republic of Korea

^f Department of Applied Chemistry, Hanyang University, Ansan, Republic of Korea

^g Department of Biochemistry & Molecular Biology, College of Medicine, Yonsei University, Seoul, Republic of Korea

Abstract

This study demonstrated the potential of 50 nm PEGylated Si NPs for high-resolution in vivo²⁹Si MR imaging, emphasizing their biocompatibility and water dispersibility. The acquisition of in vivo Si MR images using the lowest reported dose after subcutaneous and intraperitoneal administration opens new avenues for future ²⁹Si MR studies.

This article is part of the themed collection: Analyst HOT Articles 2023

Download options Please wait...

Supplementary files

Supplementary information PDF (4091K)

Article information

DOI: https://doi.org/10.1039/D3AN01395B
Article type: Communication
Submitted: 28 محرم 1445
Accepted: 07 ربيع الأول 1445
First published: 07 ربيع الأول 1445

Download Citation

Analyst, 2023,148, 5355-5360

Permissions

Request permissions

Background free in vivo²⁹Si MR imaging with hyperpolarized PEGylated silicon nanoparticles

S. Yang, J. Kim, T. G. Lee, M. Park, H. Y. Son, C. G. Joo, J. H. Shim, Y. Lee and Y. Huh, Analyst, 2023, 148, 5355 DOI: 10.1039/D3AN01395B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Analyst