Issue 15, 2023

Magnetic nanoprobe-enabled lateral flow assays: recent advances

Abstract

In recent years, magnetic nanoparticle sensor technologies have attracted considerable interest in the point-of-care-testing (POCT) field, especially in lateral flow immunoassays (LFIAs). Although the visual signal of magnetic nanoparticles is reduced during an inspection, it can be compensated for by magnetic induction, and detection results can be quantified by magnetic sensors. Sensors that use magnetic nanoparticles (MNPs) as markers can overcome the high background noise of complex samples. In this study, MNP signal detection strategies are described from the perspectives of magnetoresistance, magnetic flux, frequency mixing technology, and magnetic permeability, and the principles and development of each technology are introduced in detail. Typical applications of magnetic nanoparticle sensor technologies are introduced. By describing the advantages and limitations of different sensing strategies, we highlight the development and improvement directions of different sensing strategies. In general, the future development of magnetic nanoparticle sensor technologies will be toward intelligent, convenient, and mobile high-performance detection equipment.

Graphical abstract: Magnetic nanoprobe-enabled lateral flow assays: recent advances

Article information

Article type
Critical Review
Submitted
16 جمادى الثانية 1444
Accepted
22 رمضان 1444
First published
11 ذو القعدة 1444

Analyst, 2023,148, 3418-3431

Magnetic nanoprobe-enabled lateral flow assays: recent advances

Y. Zhao, J. Sang, Y. Fu, J. Guo and J. Guo, Analyst, 2023, 148, 3418 DOI: 10.1039/D3AN00044C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements