Issue 1, 2022

Recent advances in catalytic enantioselective direct C–H bond functionalization of electron-deficient N-containing heteroarenes

Abstract

Catalytic enantioselective direct C–H bond functionalization of electron-deficient N-containing heteroarenes represents one of the most straightforward and powerful protocols to construct diverse enantioenriched highly functionalized N-heteroarene products. Efficient catalytic systems and a variety of strategies for highly chemo- and stereoselective C–H functionalization of electron-deficient N-containing heteroarenes have been developed over the past few decades. This review summarized the rapid progress in the catalytic asymmetric C–H functionalization of N-containing heteroarenes and discussed the challenges and potential of the field in the current stage.

Graphical abstract: Recent advances in catalytic enantioselective direct C–H bond functionalization of electron-deficient N-containing heteroarenes

Article information

Article type
Review Article
Submitted
09 محرم 1443
Accepted
14 صفر 1443
First published
15 صفر 1443

Org. Chem. Front., 2022,9, 265-280

Recent advances in catalytic enantioselective direct C–H bond functionalization of electron-deficient N-containing heteroarenes

X. Liu, L. Jiang, M. Luo, Z. Ren and S. Wang, Org. Chem. Front., 2022, 9, 265 DOI: 10.1039/D1QO01223A

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