Issue 26, 2022

Introducing C2 asymmetry in chromans—a brief story

Abstract

The Trost group made notable attempts in the 1990s to synthesize several natural products such as vitamin E and its analogs, clusifoliol, rhododaurichromanic acid A, siccanin, and calanolide A and B through the palladium-catalyzed asymmetric allylic alkylation (AAA) reaction. This review highlights Prof. Trost's contributions to chroman chemistry, and specifically to the most challenging C2 asymmetry.

Graphical abstract: Introducing C2 asymmetry in chromans—a brief story

Article information

Article type
Perspective
Submitted
22 رجب 1443
Accepted
07 ذو القعدة 1443
First published
15 ذو القعدة 1443

New J. Chem., 2022,46, 12446-12455

Introducing C2 asymmetry in chromans—a brief story

S. Kundu, S. Bishi and D. Sarkar, New J. Chem., 2022, 46, 12446 DOI: 10.1039/D2NJ00944G

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