Issue 7, 2020

Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosensitizers

Abstract

In this study, we report for the first time the use of four aza-dipyrromethenes (ADPMs) as photosensitizers for cancer PDT. The synthesis and characterization of the ADPMs and their photodynamic action against B16F10 melanoma cells were assessed. ADPM 2 is the best singlet oxygen generator and the most phototoxic (at 2.5 μM) towards B16F10 cells.

Graphical abstract: Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosensitizers

Supplementary files

Article information

Article type
Paper
Submitted
02 شعبان 1441
Accepted
25 رمضان 1441
First published
26 رمضان 1441

Photochem. Photobiol. Sci., 2020,19, 885-891

Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosensitizers

K. A. D. F. Castro, L. D. Costa, S. Guieu, J. C. Biazzotto, M. D. G. P. M. S. Neves, M. A. F. Faustino, R. S. da Silva and A. C. Tomé, Photochem. Photobiol. Sci., 2020, 19, 885 DOI: 10.1039/D0PP00114G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements