Issue 19, 2020

A laccase-catalysed tyrosine click reaction

Abstract

A laccase-catalysed tyrosine click reaction proceeded between the tyrosine modification reagent N-methyl luminol and tyrosine residues in peptides/proteins. Laccase-catalysed tyrosine-specific modification under mild reaction conditions (shaking at 37 °C) was more efficient than previously reported tyrosine click reactions using hemin, horseradish peroxidase (HRP) or electrochemistry.

Graphical abstract: A laccase-catalysed tyrosine click reaction

Supplementary files

Article information

Article type
Communication
Submitted
04 شعبان 1441
Accepted
30 شعبان 1441
First published
08 رمضان 1441

Org. Biomol. Chem., 2020,18, 3664-3668

A laccase-catalysed tyrosine click reaction

S. Sato, K. Nakane and H. Nakamura, Org. Biomol. Chem., 2020, 18, 3664 DOI: 10.1039/D0OB00650E

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