Issue 17, 2018
From the journal:

RSC Advances

White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation†

Jiamei Liang,ab   Pan Wu,ab   Chunyan Tan ORCID logo *ab  and  Yuyang Jiangbc  

* Corresponding authors

a Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China

b The State Key Laboratory of Chemical Oncogenomics, The Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P. R. China
E-mail: tancy@sz.tsinghua.edu.cn
Tel: +86-755-26036533

c School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, P. R. China

Abstract

A cationic conjugated polyelectrolyte (CPE) PPET3 with a poly(p-phenylene ethynylene terthiophene) backbone and quaternary ammonium side chains was designed and synthesized. It serves as an efficient photosensitizer for photodynamic therapy under white light irradiation and induces cell death through the mitochondrial apoptosis pathway.

Graphical abstract: White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8RA00774H
Article type
Paper
Submitted
08 جمادى الأولى 1439
Accepted
09 جمادى الثانية 1439
First published
13 جمادى الثانية 1439
This article is Open Access
Creative Commons BY license

RSC Adv., 2018,8, 9218-9222

Permissions

Request permissions

White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

J. Liang, P. Wu, C. Tan and Y. Jiang, RSC Adv., 2018, 8, 9218 DOI: 10.1039/C8RA00774H

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements