Issue 14, 2018

Sulfur mediated propargylic C–H alkylation of alkynes

Abstract

A transition-metal-free, sulfur mediated propargylic C–H alkylation reaction was realized through a one-pot procedure. The reaction design involves an initial addition between alkynes and triflic anhydride activated sulfoxides, and a subsequent [2,3]-sigmatropic rearrangement of the allenyl sulfur ylides generated under basic conditions to give propargylic C–H alkylation products.

Graphical abstract: Sulfur mediated propargylic C–H alkylation of alkynes

Supplementary files

Article information

Article type
Research Article
Submitted
07 شعبان 1439
Accepted
20 رمضان 1439
First published
21 رمضان 1439

Org. Chem. Front., 2018,5, 2167-2170

Sulfur mediated propargylic C–H alkylation of alkynes

G. Hu, J. Xu and P. Li, Org. Chem. Front., 2018, 5, 2167 DOI: 10.1039/C8QO00410B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements