Issue 13, 2018

A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

Abstract

After a serendipitous synthesis of a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas, a more reliable synthetic method is now described using our building blocks containing stereodefined stereochemistry at C-20.

Graphical abstract: A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

Supplementary files

Article information

Article type
Research Article
Submitted
17 رجب 1439
Accepted
23 شعبان 1439
First published
25 شعبان 1439

Org. Chem. Front., 2018,5, 2016-2019

A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

H. Santalla, F. Garrido, G. Gómez and Y. Fall, Org. Chem. Front., 2018, 5, 2016 DOI: 10.1039/C8QO00338F

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