Issue 1, 2018

Scandium-catalyzed C(sp3)–H alkylation of N,N-dimethyl anilines with alkenes

Abstract

A scandium complex based on a new type of tridentate ligand enabled an atom- and step-economical C(sp3)–H addition of N,N-dimethyl anilines to a variety of unactivated alkenes affording branched products for the first time. A cationic o-dimethylaminophenyl scandium species was isolated and confirmed as the catalytic intermediate in this transformation.

Graphical abstract: Scandium-catalyzed C(sp3)–H alkylation of N,N-dimethyl anilines with alkenes

Supplementary files

Article information

Article type
Research Article
Submitted
22 ذو القعدة 1438
Accepted
28 ذو الحجة 1438
First published
29 ذو الحجة 1438

Org. Chem. Front., 2018,5, 59-63

Scandium-catalyzed C(sp3)–H alkylation of N,N-dimethyl anilines with alkenes

H. Gao, J. Su, P. Xu and X. Xu, Org. Chem. Front., 2018, 5, 59 DOI: 10.1039/C7QO00718C

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