Issue 91, 2017
From the journal:

Chemical Communications

Modular synthesis of thirty lead-like scaffolds suitable for CNS drug discovery†

Joan Mayol-Llinàs, ORCID logo a   William Farnaby‡b  and  Adam Nelson ORCID logo *ac  

* Corresponding authors

a School of Chemistry, University of Leeds, UK
E-mail: a.s.nelson@leeds.ac.uk

b Takeda Cambridge, Unit 418, Cambridge Science Park, Milton Road, Cambridge, UK

c Astbury Centre for Structural Molecular Biology, University of Leeds, UK

Abstract

A modular synthetic approach was developed that yielded thirty diverse lead-like scaffolds suitable for CNS drug discovery.

Graphical abstract: Modular synthesis of thirty lead-like scaffolds suitable for CNS drug discovery

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Article information

DOI
https://doi.org/10.1039/C7CC06078E
Article type
Communication
Submitted
11 ذو القعدة 1438
Accepted
29 ذو الحجة 1438
First published
14 صفر 1439
This article is Open Access
Creative Commons BY license

Chem. Commun., 2017,53, 12345-12348

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Modular synthesis of thirty lead-like scaffolds suitable for CNS drug discovery

J. Mayol-Llinàs, W. Farnaby and A. Nelson, Chem. Commun., 2017, 53, 12345 DOI: 10.1039/C7CC06078E

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