Issue 87, 2017

Programmable fusion of liposomes mediated by lipidated PNA

Abstract

We recently reported a DNA-programmed fusion cascade enabling the use of liposomes as nanoreactors for compartmentalized chemical reactions. This communication reports an alternative and robust strategy based on lipidated peptide nucleic acids (LiPs). LiPs enabled fusion of liposomes with remarkable 31% efficiency at 50 °C with low leakage (5%).

Graphical abstract: Programmable fusion of liposomes mediated by lipidated PNA

Supplementary files

Article information

Article type
Communication
Submitted
11 ذو القعدة 1438
Accepted
21 محرم 1439
First published
21 محرم 1439

Chem. Commun., 2017,53, 11921-11924

Programmable fusion of liposomes mediated by lipidated PNA

A. Rabe, P. M. G. Löffler, O. Ries and S. Vogel, Chem. Commun., 2017, 53, 11921 DOI: 10.1039/C7CC06058K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements