Issue 38, 2016

Diselenide-based probe for the selective imaging of hypochlorite in living cancer cells

Abstract

A non-traditional and robust probe skeleton was derivatized for chemosensing applications to investigate a potential novel mode of hypochlorite detection. The BDPP-DSe probe gave a ∼180-fold “turn-on” response to hypochlorite. Confocal fluorescence imaging demonstrated detection of hypochlorite in living cells and cell membrane permeability.

Graphical abstract: Diselenide-based probe for the selective imaging of hypochlorite in living cancer cells

Supplementary files

Article information

Article type
Communication
Submitted
08 جمادى الأولى 1437
Accepted
13 جمادى الثانية 1437
First published
15 جمادى الثانية 1437

RSC Adv., 2016,6, 32013-32017

Diselenide-based probe for the selective imaging of hypochlorite in living cancer cells

Y. Kim, M. Choi, S. T. Manjare, S. Jon and D. G. Churchill, RSC Adv., 2016, 6, 32013 DOI: 10.1039/C6RA04257K

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