Issue 2, 2015

Transition metal-catalyzed direct remote C–H functionalization of alkyl groups via C(sp3)–H bond activation

Abstract

This review is focused on the recent advances in the transition metal-catalyzed direct remote C–H-functionalization of alkyl groups via C(sp3)–H bond activation. In general, carboxamide/ester-chelated β-functionalization reactions are summarized, which mainly include direct β-arylation, β-alkylation, β-alkynylation, etc. Additionally, some biologically interesting architectures are constructed by using these direct β-functionalization reactions.

Graphical abstract: Transition metal-catalyzed direct remote C–H functionalization of alkyl groups via C(sp3)–H bond activation

Associated articles

Article information

Article type
Review Article
Submitted
27 رمضان 1435
Accepted
06 صفر 1436
First published
09 صفر 1436

Org. Chem. Front., 2015,2, 169-178

Transition metal-catalyzed direct remote C–H functionalization of alkyl groups via C(sp3)–H bond activation

G. Qiu and J. Wu, Org. Chem. Front., 2015, 2, 169 DOI: 10.1039/C4QO00207E

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