Issue 7, 2014

Chopping unfunctionalized carbon–carbon bonds: a new paradigm for the synthesis of organonitriles

Abstract

In the last year, a new strategy for the synthesis of organonitriles, whether aliphatic or aromatic, has emerged based on the direct carbon–carbon double or triple bond cleavage of alkenyl or alkynyl precursors. This Highlight mainly focuses on the efforts made, often nearly simultaneously, by three research teams that shaped the implementation of this new paradigm, which should be of great value for the synthetic community facing the ever-growing demand for new organonitriles, especially in medicinal chemistry.

Graphical abstract: Chopping unfunctionalized carbon–carbon bonds: a new paradigm for the synthesis of organonitriles

Article information

Article type
Highlight
Submitted
29 رجب 1435
Accepted
21 شعبان 1435
First published
22 شعبان 1435

Org. Chem. Front., 2014,1, 825-833

Author version available

Chopping unfunctionalized carbon–carbon bonds: a new paradigm for the synthesis of organonitriles

P. Bisseret, G. Duret and N. Blanchard, Org. Chem. Front., 2014, 1, 825 DOI: 10.1039/C4QO00158C

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