Issue 20, 2014

Convergent routes to substituted naphthylamides

Abstract

Practical, convergent routes to variously substituted 1- and 2-naphthylamides have been developed. They exploit the ability of xanthates to undergo both intermolecular radical additions to vinyl pivalate and intramolecular radical cyclisations to aromatic rings. In the case of 1-naphthylamides, the existence of an intramolecular hydrogen bond was used to facilitate the cyclisation step.

Graphical abstract: Convergent routes to substituted naphthylamides

Supplementary files

Article information

Article type
Paper
Submitted
13 ربيع الثاني 1435
Accepted
12 جمادى الأولى 1435
First published
12 جمادى الأولى 1435

Org. Biomol. Chem., 2014,12, 3251-3264

Convergent routes to substituted naphthylamides

N. D. M. Tran and S. Z. Zard, Org. Biomol. Chem., 2014, 12, 3251 DOI: 10.1039/C4OB00339J

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