Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation

Sandani Samarajeewa; Ryan P. Zentay; Nema D. Jhurry; Ang Li; Kellie Seetho; Jiong Zou; Karen L. Wooley

doi:10.1039/C3CC46013D

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation†

Sandani Samarajeewa,^a Ryan P. Zentay,^a Nema D. Jhurry,^a Ang Li,^a Kellie Seetho,^a Jiong Zou^a and Karen L. Wooley*^a

Author affiliations

* Corresponding authors

^a Departments of Chemistry and Chemical Engineering, Texas A&M University, P. O. Box 30012, College Station, Texas, USA
E-mail: wooley@chem.tamu.edu
Fax: +1 (979) 862-1137
Tel: +1 (979) 845-4077

Abstract

Electrostatic interaction-mediated enzymatic-hydrolysis of poly(lactide)-containing nanoscale assemblies is described. At physiological pH, degradable core–shell morphologies with charged shells can readily attract or repel enzymes carrying opposite or similar charges, respectively.

This article is part of the themed collection: Celebrating the ChemComm Emerging Investigator Lectureship Winners

Download options Please wait...

Supplementary files

Supplementary information PDF (504K)

Article information

DOI: https://doi.org/10.1039/C3CC46013D
Article type: Communication
Submitted: 29 رمضان 1434
Accepted: 22 محرم 1435
First published: 01 صفر 1435

Download Citation

Chem. Commun., 2014,50, 968-970

Permissions

Request permissions

Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation

S. Samarajeewa, R. P. Zentay, N. D. Jhurry, A. Li, K. Seetho, J. Zou and K. L. Wooley, Chem. Commun., 2014, 50, 968 DOI: 10.1039/C3CC46013D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation

Social activity

Search articles by author

Spotlight

Advertisements