Issue 45, 2009
From the journal:

Chemical Communications

Solid-phase synthesis of protected α-amino phosphonic acid oligomers†‡

Yoshitaka Ishibashia  and  Masato Kitamura*a  

* Corresponding authors

a Research Center for Materials Science and the Department of Chemistry, Nagoya University, Chikusa, Japan
E-mail: kitamura@os.rcms.nagoya-u.ac.jp
Fax: +81 52-789-2958

Abstract

By establishing both a highly efficient phosphonamidate formation and a RuCp-catalyzed cleavage of an allyl linker, the solid-phase synthesis of Fmoc-(GlyP(OBn))6-OH/DIEA, a protected form of a new type of unnatural peptide α-amino phosphonic acid oligomer (APO), has been realized.

Graphical abstract: Solid-phase synthesis of protected α-amino phosphonic acid oligomers

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Article information

DOI
https://doi.org/10.1039/B912231A
Article type
Communication
Submitted
29 جمادى الثانية 1430
Accepted
11 شوال 1430
First published
25 شوال 1430

Chem. Commun., 2009, 6985-6987

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Solid-phase synthesis of protected α-amino phosphonic acid oligomers

Y. Ishibashi and M. Kitamura, Chem. Commun., 2009, 6985 DOI: 10.1039/B912231A

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