Issue 5, 2021

Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity

Abstract

A series of fluorescent molecular rotors, acridinium benzoates (Acr-A,B,C,D), were designed for ratiometrically monitoring cellular viscosity. High sensitivity to viscosity was observed in probe Acr-A with an insignificant steric effect in the acridinium nitrogen. Acr-A was employed to distinguish cancer cells from normal cells and track the dynamics of viscosity during cellular apoptosis.

Graphical abstract: Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity

Supplementary files

Article information

Article type
Communication
Submitted
18 ربيع الثاني 1442
Accepted
27 جمادى الأولى 1442
First published
27 جمادى الأولى 1442

Analyst, 2021,146, 1538-1542

Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity

M. Wen, C. Li, M. Zhang, Y. Sun, F. Liu, X. Cui and Y. Shan, Analyst, 2021, 146, 1538 DOI: 10.1039/D0AN02321C

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