Issue 16, 2020

Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects

Abstract

Ultrasensitive and highly accurate bioassays are critically required for the early detection of various biomarkers and diagnosis of cancer. Electrogenerated chemiluminescence (ECL) is one such technique which shows powerful analytical ability by incorporating ECL active species for sensitive detection of targets. In this regard, the development of ECL as an assay technique is constantly being pushed for better performance and lower detection limits. Incorporation of sensitive immunosensing and aptasensing methods with ECL has the ability to multiply the advantages several-fold. The recent progress in and methods utilized for the enhancement and amplification of ECL detection techniques based on highly sensitive immunosensors and aptasensors have been discussed in this review with regard to widely popular techniques.

Graphical abstract: Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects

Article information

Article type
Review Article
Submitted
18 ربيع الأول 1441
Accepted
09 جمادى الثانية 1441
First published
10 جمادى الثانية 1441

J. Mater. Chem. B, 2020,8, 3192-3212

Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects

R. A. Husain, S. R. Barman, S. Chatterjee, I. Khan and Z. Lin, J. Mater. Chem. B, 2020, 8, 3192 DOI: 10.1039/C9TB02578B

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