Issue 5, 2019

Synthesis and scale-up of water-soluble quaternary cationic monomers in a continuous flow system

Abstract

A continuous flow technology was developed for the synthesis and scale-up of water-soluble quaternary cationic monomers represented by dimethyldiallylammonium chloride (DMDAAC) in a self-designed reactor. For industrial applications, static mixers were employed in a self-designed scaled-up reactor to maintain the mass and heat transfer rates from microfluidics to mesofluidics during the scale-up. Three different types of static mixers were investigated, and their optimal combination was determined. Various factors including the reaction temperature, fluid rate, and reagent concentration were also investigated in detail. This work increased the yield up to 92% under optimal conditions with an output of one kiloton per year. Moreover, this proposed method exhibited excellent performance in the synthesis and scale-up of other water-soluble quaternary cationic monomers in a continuous flow system.

Graphical abstract: Synthesis and scale-up of water-soluble quaternary cationic monomers in a continuous flow system

Article information

Article type
Paper
Submitted
11 ربيع الثاني 1440
Accepted
20 جمادى الثانية 1440
First published
21 جمادى الثانية 1440

React. Chem. Eng., 2019,4, 919-926

Synthesis and scale-up of water-soluble quaternary cationic monomers in a continuous flow system

Z. Fang, Y. Yang, J. Gu, Z. Yang, F. Dai, H. Zheng, W. He, C. Liu, N. Zhu and K. Guo, React. Chem. Eng., 2019, 4, 919 DOI: 10.1039/C8RE00335A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements