An effective approach to aryl-substituted propanoic acids via the Pd-catalyzed hydrocarboxylation of stilbenes

Jie Dai; Wenlong Ren; Jingfu Li; Yian Shi

doi:10.1039/C7QO00726D

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An effective approach to aryl-substituted propanoic acids via the Pd-catalyzed hydrocarboxylation of stilbenes†

Jie Dai,

^a Wenlong Ren,^a Jingfu Li

^a and Yian Shi*^ab

Author affiliations

* Corresponding authors

^a State Key Laboratory of Coordination Chemistry, Center for Multimolecular Organic Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China

^b Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA
E-mail: Yian.Shi@colostate.edu

Abstract

An effective Pd(0)-catalyzed hydrocarboxylation of substituted stilbenes with formic acid and HCOOPh is described. A variety of aryl-substituted propanoic acids are obtained in good yields without using external toxic CO gas.

This article is part of the themed collections: Organic Chemistry Frontiers HOT articles for 2018 and Organic Chemistry Frontiers HOT articles for 2017

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Article information

DOI: https://doi.org/10.1039/C7QO00726D
Article type: Research Article
Submitted: 24 ذو القعدة 1438
Accepted: 07 محرم 1439
First published: 19 محرم 1439

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Org. Chem. Front., 2018,5, 561-565

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An effective approach to aryl-substituted propanoic acids via the Pd-catalyzed hydrocarboxylation of stilbenes

J. Dai, W. Ren, J. Li and Y. Shi, Org. Chem. Front., 2018, 5, 561 DOI: 10.1039/C7QO00726D

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Organic Chemistry Frontiers

An effective approach to aryl-substituted propanoic acids via the Pd-catalyzed hydrocarboxylation of stilbenes†

Abstract

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An effective approach to aryl-substituted propanoic acids via the Pd-catalyzed hydrocarboxylation of stilbenes

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