Issue 7, 2017

Recent advances in positional-selective alkenylations: removable guidance for twofold C–H activation

Abstract

The transition metal-catalyzed transformation of otherwise inert C–H bonds into substituted alkenes offers a versatile tool for the synthesis of value added olefinic molecules. Recent developments in the directing group assisted C–H activation approach ensured high levels of positional selectivity. A vast number of coordinating groups have been utilized in directed C–H alkenylation, which are often not removable after the desired transformation. However, the concept of easily removable or traceless directing group strategy overcomes this limitation and enables site-selective C–H alkenylation of relevance to academia and the practitioners in industry. Various easily removable or transformable directing groups utilized in the transition metal-catalyzed oxidative C–H alkenylations are discussed in this review until February 2017.

Graphical abstract: Recent advances in positional-selective alkenylations: removable guidance for twofold C–H activation

Article information

Article type
Review Article
Submitted
20 جمادى الأولى 1438
Accepted
14 جمادى الثانية 1438
First published
25 جمادى الثانية 1438

Org. Chem. Front., 2017,4, 1435-1467

Recent advances in positional-selective alkenylations: removable guidance for twofold C–H activation

W. Ma, P. Gandeepan, J. Li and L. Ackermann, Org. Chem. Front., 2017, 4, 1435 DOI: 10.1039/C7QO00134G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements