Synthesis of novel N-troponyl oxalamides by Pd(II)-catalyzed C(sp3)–H functionalization of N-troponyl glycinates via β-hydride elimination at the Pd-complex. These oxalamides form distinctive β-sheet type structures owing to the troponyl carbonyl.
We present a novel, eco-friendly and one-pot approach for synthesizing unsymmetrical oxalamides with the aid of dichloroacetamide and amine/amides in the presence of CBr4 in a basic medium.
A ruthenium pincer-catalyzed dehydrogenative coupling of ethylene glycol and amines forms oxalamides, a key motif in biologically active compounds. DFT calculations reveal the rate-determining step involves hydrogen release.
We describe the synthesis of a symmetrical N,N′-bis(3-(1H-imidazol-1-yl)propyl)oxalamide-based receptor OX(PID)2 and its characterization by different physicochemical techniques, namely FT-IR, 1H and 13C NMR, TGA, and mass spectrometry.
A novel oxalamide ligand with additional coordinating groups was developed for the coupling of (hetero)aryl bromides with both alcohols and phenols.