An efficient and environmentally friendly for the synthesis of symmetrical and unsymmetrical difluoromethylated diarylmethanes via direct bisarylation of difluoroacetaldehyde hemiacetal with aniline enabled by HFIP–B(C6F5)3 adduct is described.
In this review, we summarize various strategies for constructing CF2H groups based on different approaches, resulting in a series of difluoromethyl derivatives.
Novel bis(indolyl)methanes has been synthesized in satisfactory isolated yields using carbohydrate-derived 5-substituted-2-furaldehydes as renewable reactants and gluconic acid aqueous solution as a sustainable catalyst.
Bis(3-indolyl)methanes (BIMs) are known for their important bioactivities, which include anti-cancer, anti-inflammatory, antibacterial, and antioxidant properties.
This review article highlights the recent advances of transition-metal-catalyzed interrupted borrowing hydrogen (IBH) catalysis and its applications in the sustainable and affordable chemical synthesis using alcohols as C1 feedstocks.