Phosphorescent iridium complexes activated by endogenous zinc as a mitochondrial DNA nuclease for stimulation of the cGAS-STING pathway

Zhi-Yuan Li, Long-Bo Yu, Qing-Hua Shen, Liang Hao, Peng Wang, Xiao-Xiao Chen, Yu-Yi Ling and Cai-Ping Tan

Chem. Sci., 2026, 17, 1721
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Optimizing mitochondrial-targeting groups of positively-charged BODIPY nanoparticles for enhanced photodynamic therapy

Huixuan Qi, Ruobing Qu, Jiaping Shen, Hui Wen, Chunyu Yuan, Wenhai Lin, Tingting Sun and Min Li

Mater. Chem. Front., 2024, 8, 3898
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Guanine nucleotide directed co-assembly with Pt-complexes for tailoring chiroptical properties and multimodal molecular recognition

Jiannan Xiao, Fang Zeng, Zhi-Wang Luo, Bo Yang, Jun Song, Pengfei Duan, Xue Jin, Yong Chen and Zhen-Qiang Yu

Chem. Sci., 2026, 17, 1330
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G-quadruplex-guided bifunctional platinum complexes induce multiple pyroptosis pathways for antitumor therapy

Tian-Zhu Ma, Liu-Yi Liu, You-Liang Zeng, Ke Ding, Wenting Liu, Xushen Xiong and Zong-Wan Mao

Inorg. Chem. Front., 2025, 12, 707
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Polypyridyl ruthenium(ii) complexes functionalized with fatty acids for photodynamic therapy and induction of pyroptosis

Yuan Xu, Yatao Hu, Jiaping Cao, Dixin Lin, Qiqi Zhong, Yi Wang, Hongdong Shi and Qianling Zhang

Dalton Trans., 2025, 54, 17121
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A state-of-the-art view: G-quadruplex-targeting for platinum complexes’ treatment of tumors

Jinrong Yang, Yu Chen and Hui Chao

RSC Chem. Biol., 2025, 6, 1034
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Metal Complexes Stimulating Immunogenic Pyroptosis as Burgeoning Antitumor Strategy

Yue Zheng, Kun Peng, Qian Cao and Zong‐Wan Mao

Angew Chem Int Ed, 2025, 64
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Solution structures and effects of a platinum compound successively bound MYC G-quadruplex

Wenting Liu, Bo-Chen Zhu, Liu-Yi Liu, Xiao- Yu Xia, Jinho Jang, Jonathan Dickerhoff, Danzhou Yang and Zong-Wan Mao

Nucleic Acids Research, 2024, 52, 9397
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Iridium(III) Photosensitizers Induce Simultaneous Pyroptosis and Ferroptosis for Multi‐Network Synergistic Tumor Immunotherapy

You‐Liang Zeng, Liu‐Yi Liu, Tian‐Zhu Ma, Yu Liu, Bin Liu, Wenting Liu, Qing‐Hua Shen, Chao Wu and Zong‐Wan Mao

Angew Chem Int Ed, 2024, 63
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Iridium(III) Photosensitizers Induce Simultaneous Pyroptosis and Ferroptosis for Multi‐Network Synergistic Tumor Immunotherapy

You‐Liang Zeng, Liu‐Yi Liu, Tian‐Zhu Ma, Yu Liu, Bin Liu, Wenting Liu, Qing‐Hua Shen, Chao Wu and Zong‐Wan Mao

Angewandte Chemie, 2024, 136
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Spectroscopic studies and Non-Linear optical response through C/N replacement and modulation of electron Donor/Acceptor Units on naphthyridine derivatives

Afifa Yousuf, Asad Ullah, Syeda Qirat Ul Hussain, Muhammad Arif Ali and Muhammad Arshad

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 329, 125582
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APE1 condensation in nucleoli of non-cancer cells depends on rRNA transcription and forming G-quadruplex RNA structures

Giuseppe Dall’Agnese, Nancy M Hannett, Kalon J Overholt, Jesse M Platt, Jonathan E Henninger, Asier Marcos-Vidal, Zahraa Othman, Gilmar Salgado, Giulia Antoniali and Gianluca Tell

Nucleic Acids Research, 2025, 53
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G-Quadruplexes in Tumor Immune Regulation: Molecular Mechanisms and Therapeutic Prospects in Gastrointestinal Cancers

Yunxia Zhou, Difei Xu, Ying Zhang and Huaixiang Zhou

Biomedicines, 2025, 13, 1057
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The G-quadruplex ligand CX-5461: an innovative candidate for disease treatment

Hong-Xia Li, Yi-Meng He, Jing Fei, Man Guo, Chen Zeng, Pi-Jun Yan, Yong Xu, Gang Qin and Fang-Yuan Teng

J Transl Med, 2025, 23
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Recent Progress and Potential of G4 Ligands in Cancer Immunotherapy

Jiahui Lin, Zhu Gong, Yingyue Lu, Jiongheng Cai, Junjie Zhang, Jiaheng Tan, Zhishu Huang and Shuobin Chen

Molecules, 2025, 30, 1805
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Development and In Vitro Evaluation of [64Cu]Cu-NOTA-TP-PSMA, a Novel Radiotheranostic Agent Against Prostate Cancer

Hoda Talebian, Samia Ait-Mohand, Prenitha Mercy Ignatius Arokia Doss, Léon Sanche and Brigitte Guérin

IJMS, 2025, 26, 11651
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Metal Complexes Stimulating Immunogenic Pyroptosis as Burgeoning Antitumor Strategy

Yue Zheng, Kun Peng, Qian Cao and Zong‐Wan Mao

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202507186

Exploring the role of G-quadruplex DNA, and their structural polymorphism, in targeting small molecules for the design of anticancer therapeutics: Progress, challenges, and future directions

Soma Roy, Pulakesh Pramanik and Santanu Bhattacharya

Biochimie, 2025, 234, 120
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Sensitization of melanoma cells to standard chemotherapy: G-quadruplex binders as synergistic agents

Carolina Persico, Nunzia Iaccarino, Francesca Romano, Mariateresa Giustiniano, Camilla Russo, Sonia Laneri, Ritamaria Di Lorenzo, Immacolata Aiello, Sara Abate, Luana Izzo, Francesco Merlino, Diego Brancaccio, Bruno Pagano, Jussara Amato, Simona Marzano, Federica D’Aria, Stefano De Tito, Anna Di Porzio and Antonio Randazzo

NAR Cancer, 2024, 6
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Decoding the prospective of metal complexes in anti-cancer therapeutics by targeting of G-quadruplex DNA

Pulakesh Pramanik and Santanu Bhattacharya

Journal of Inorganic Biochemistry, 2025, 270, 112947
DOI: 10.1016/j.jinorgbio.2025.112947

Anticancer activity of new oxaliplatin analogs with aliphatic glycine ligands

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Journal of Molecular Liquids, 2026, 129447
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