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DOI: 10.1039/D3MD00690E

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DOI: 10.1039/D4MD00860J

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DOI: 10.1016/j.ejmech.2023.115413

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DOI: 10.1016/j.micpath.2025.107861

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DOI: 10.1021/acsinfecdis.3c00436

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DOI: 10.1016/j.tig.2024.08.002

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DOI: 10.1155/2022/3368883

Early Staphylococcal Periprosthetic Joint Infection (PJI) Treated with Debridement, Antibiotics, and Implant Retention (DAIR): Inferior Outcomes in Patients with Staphylococci Resistant to Rifampicin

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Antibiotics, 2023, 12, 1589
DOI: 10.3390/antibiotics12111589

Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against Enterobacter

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DOI: 10.1021/acsinfecdis.2c00446

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DOI: 10.1016/j.tice.2023.102097

Sulfonamidyl derivatives of sigmacidin: Protein-protein interaction inhibitors targeting bacterial RNA polymerase and sigma factor interaction exhibiting antimicrobial activity against antibiotic-resistant bacteria

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DOI: 10.1016/j.bioorg.2023.106983

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DOI: 10.3390/pharmaceutics15010131

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DOI: 10.3390/ph15070804

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DOI: 10.1002/cbdv.202400267

How to Shut Down Transcription in Archaea during Virus Infection

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DOI: 10.3390/microorganisms10091824

Bacteriophage RNA polymerases: catalysts for mRNA vaccines and therapeutics

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