Vancomycin-loaded titanium coatings with an interconnected micro-patterned structure for prophylaxis of infections: an in vivo study

Hao Zhang, Guangchao Wang, Peizhao Liu, Dake Tong, Chen Ding, Zequan Zhang, Youtao Xie, Hao Tang and Fang Ji

RSC Adv., 2018, 8, 9223
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Micro-patterned titanium coatings with a grid-like structure doped with vancomycin against bacteria and affecting osteogenic differentiation

Guangchao Wang, Hao Zhang, Qianyun He, Dake Tong, Chen Ding, Peizhao Liu, Zequan Zhang, Youtao Xie and Fang Ji

RSC Adv., 2017, 7, 19565
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The antimicrobial peptide KR-12 promotes the osteogenic differentiation of human bone marrow stem cells by stimulating BMP/SMAD signaling

Hui Li, Shutao Zhang, Bin'en Nie, Zhe Du, Teng Long and Bing Yue

RSC Adv., 2018, 8, 15547
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A comparative analysis of antibacterial properties and inflammatory responses for the KR-12 peptide on titanium and PEGylated titanium surfaces

Bin'en Nie, Teng Long, Hui Li, Xiaojie Wang and Bing Yue

RSC Adv., 2017, 7, 34321
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Antimicrobial peptide-based materials: opportunities and challenges

Akhilesh Rai, Rafaela Ferrão, Paulo Palma, Tatiana Patricio, Paula Parreira, Elsa Anes, Chiara Tonda-Turo, M. Cristina L. Martins, Nuno Alves and Lino Ferreira

J. Mater. Chem. B, 2022, 10, 2384
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KR-12 coating of polyetheretherketone (PEEK) surface via polydopamine improves osteointegration and antibacterial activity in vivo

Xiangchao Meng, Jue Zhang, Jun Chen, Binen Nie, Bing Yue, Wei Zhang, Zhuocheng Lyu, Teng Long and You Wang

J. Mater. Chem. B, 2020, 8, 10190
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Peptide platform for 3D-printed Ti implants with synergistic antibacterial and osteogenic functions to enhance osseointegration

Chenying Cui, Yifan Zhao, Jingyu Yan, Ziyang Bai, Guning Wang, Yingyu Liu, Yurong Xu, Lihong Zhou, Kaifang Zhang, Yanling Mi, Binbin Zhang, Xiuping Wu and Bing Li

Materials Today Bio, 2025, 30, 101430
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The Potential of Surface-Immobilized Antimicrobial Peptides for the Enhancement of Orthopaedic Medical Devices: A Review

Barbara Skerlavaj and Gerard Boix-Lemonche

Antibiotics, 2023, 12, 211
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Covalent Immobilization of Enoxacin onto Titanium Implant Surfaces for Inhibiting Multiple Bacterial Species Infection and In Vivo Methicillin-Resistant Staphylococcus aureus Infection Prophylaxis

Bin'en Nie, Teng Long, Haiyong Ao, Jianliang Zhou, Tingting Tang and Bing Yue

Antimicrob Agents Chemother, 2017, 61
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Combating Implant Infections: Shifting Focus from Bacteria to Host

Saber Amin Yavari, Suzanne M. Castenmiller, Jos A. G. van Strijp and Michiel Croes

Advanced Materials, 2020, 32
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Origami of KR-12 Designed Antimicrobial Peptides and Their Potential Applications

Jayaram Lakshmaiah Narayana, Abraham Fikru Mechesso, Imran Ibni Gani Rather, D. Zarena, Jinghui Luo, Jingwei Xie and Guangshun Wang

Antibiotics, 2024, 13, 816
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Titanium surfaces immobilized with the major antimicrobial fragment FK-16 of human cathelicidin LL-37 are potent against multiple antibiotic-resistant bacteria

Biswajit Mishra and Guangshun Wang

Biofouling, 2017, 33, 544
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Phosphorylcholine and KR12-Containing Corneal Implants in HSV-1-Infected Rabbit Corneas

Kamal Malhotra, Oleksiy Buznyk, Mohammad Mirazul Islam, Elle Edin, Sankar Basu, Marc Groleau, Delali Shana Dégué, Per Fagerholm, Adrien Fois, Sylvie Lesage, Jaganmohan R. Jangamreddy, Egidijus Šimoliūnas, Aneta Liszka, Hirak K. Patra and May Griffith

Pharmaceutics, 2023, 15, 1658
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Approaches based on passive and active antibacterial coating on titanium to achieve antibacterial activity

Sheng Qin, Kaihang Xu, Binen Nie, Fang Ji and Hao Zhang

J Biomedical Materials Res, 2018, 106, 2531
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Functionalization of titanium using KR-12 peptide: antibacterial and osteogenic properties

Emine Afra Demirci, Sakip Önder, Tayfun Acar, Nisa Irem Büyük, Selin Zeynep Sunar and Gamze Torun Köse

Surface Innovations, 2025, 13, 128
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Engineering quaternized chitosan in the 3D bacterial cellulose structure for antibacterial wound dressings

Haiyong Ao, Wenwen Jiang, Yanjiao Nie, Chen Zhou, Jiajia Zong, Mingzhuo Liu, Xuqiang Liu and Yizao Wan

Polymer Testing, 2020, 86, 106490
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Utilization of antimicrobial peptides, analogues and mimics in creating antimicrobial surfaces and bio-materials

Ingrid Batista Pinto, Leandro dos Santos Machado, Beatriz Torres Meneguetti, Micaella Lima Nogueira, Cristiano Marcelo Espínola Carvalho, Antonia Railda Roel and Octávio Luiz Franco

Biochemical Engineering Journal, 2019, 150, 107237
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Fabrication of gentamicin loaded Col-I/HA multilayers modified titanium coatings for prevention of implant infection

Le Ma, Jiajia Zong, Xiaowei Xun, Xiaoming Hu, Zejing Chen, Quanchao Zhang, Mengxia Peng, Botao Song and Haiyong Ao

Front. Chem., 2022, 10
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Immobilizing bacitracin on titanium for prophylaxis of infections and for improving osteoinductivity: An in vivo study

Bin’en Nie, Haiyong Ao, Teng Long, Jianliang Zhou, Tingting Tang and Bing Yue

Colloids and Surfaces B: Biointerfaces, 2017, 150, 183
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Application of Antimicrobial Peptides (AMPs) in Treatment of Osteomyelitis in Human and Veterinary Orthopedics

Dominika Nguyen Ngoc, Michał Latalski, Anna Danielewicz, Tomasz Szponder, Joanna Wessely-Szponder and Ewa Mazur

JFB, 2025, 16, 90
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Antimicrobial Peptides in the Battle against Orthopedic Implant-Related Infections: A Review

Bruna Costa, Guillermo Martínez-de-Tejada, Paula A. C. Gomes, M. Cristina L. Martins and Fabíola Costa

Pharmaceutics, 2021, 13, 1918
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Macrophage polarization, inflammatory signaling, and NF-κB activation in response to chemically modified titanium surfaces

Hao Zhang, Xuelin Wu, Guangchao Wang, Peizhao Liu, Sheng Qin, Kaihang Xu, Dake Tong, Hong Ding, Hao Tang and Fang Ji

Colloids and Surfaces B: Biointerfaces, 2018, 166, 269
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KR12 peptide-modified ECM coating for enhanced osteogenic and antimicrobial activity of titanium surfaces

Emine Afra Demirci, Sakip Önder, Tayfun Acar, Selin Zeynep Sunar and Gamze Torun Köse

Biomaterials Advances, 2026, 179, 214515
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Optimised amine density via plasma treatment for covalent immobilisation of AMPs to promote osteoblasts and enhance antimicrobial activity

Mohadeseh Zare, Bogdan Butoi, Corneliu Porosnicu, Ion N. Mihailescu, David Grossin, Sarah A. Kuehne, Zubair Ahmed and Artemis Stamboulis

Colloids and Surfaces B: Biointerfaces, 2026, 257, 115188
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De novo strategy with engineering a multifunctional bacterial cellulose-based dressing for rapid healing of infected wounds

Chen Zhou, Zhifei Yang, Xiaowei Xun, Le Ma, Zejing Chen, Xiaoming Hu, Xidong Wu, Yizao Wan and Haiyong Ao

Bioactive Materials, 2022, 13, 212
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Antibacterial peptides-loaded bioactive materials for the treatment of bone infection

Gan Wang, Yutao Cui, He Liu, Yuhang Tian, Shaorong Li, Yi Fan, Shouye Sun, Dankai Wu and Chuangang Peng

Colloids and Surfaces B: Biointerfaces, 2023, 225, 113255
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Physical behavior of KR-12 peptide on solid surfaces and Langmuir-Blodgett lipid films: Complementary approaches to its antimicrobial mode against S. aureus

Katerine Chanci, Johnatan Diosa, Marco A. Giraldo and Monica Mesa

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2022, 1864, 183779
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Covalent grafting of titanium with a cathelicidin peptide produces an osteoblast compatible surface with antistaphylococcal activity

Gerard Boix-Lemonche, Jordi Guillem-Marti, Francesca D’Este, José María Manero and Barbara Skerlavaj

Colloids and Surfaces B: Biointerfaces, 2020, 185, 110586
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Self-assembling antimicrobial peptides on nanotubular titanium surfaces coated with calcium phosphate for local therapy

Hilal Yazici, Gizem Habib, Kyle Boone, Mustafa Urgen, Feride Sermin Utku and Candan Tamerler

Materials Science and Engineering: C, 2019, 94, 333
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Dhvar5-chitosan nanogels and their potential to improve antibiotics activity

B. Costa, P.M. Alves, D.R. Fonseca, F. Campos, A.C. Monteiro, H. Shahrour, A. Gomes, F. Costa, P. Gomes, G. Martínez-de-Tejada, C. Monteiro and M.C.L. Martins

International Journal of Biological Macromolecules, 2024, 277, 134059
DOI: 10.1016/j.ijbiomac.2024.134059

Hip and Knee Section, Prevention, Prosthesis Factors: Proceedings of International Consensus on Orthopedic Infections

Craig A. Aboltins, Valentin Antoci, Sanjib Bhattacharyya, Michael Cross, Paul Ducheyne, Andrew A. Freiberg, Nils Hailer, Peter Kay, Constantinos Ketonis, Mitchell R. Klement, Nusret Köse, Mel Lee, Philip Mitchell, Sumon Nandi, Julio César Palacio, Kevin Perry, Hernan Prieto, AliSina Shahi, Richard Trebše, David Turner, Chen-Ta Wu and Hamidreza Yazdi

The Journal of Arthroplasty, 2019, 34, S309
DOI: 10.1016/j.arth.2018.09.016