New insights of Raman spectroscopy for oral clinical applications

Luis Felipe das Chagas e Silva de Carvalho and Marcelo Saito Nogueira

Analyst, 2018, 143, 6037
DOI: 10.1039/C8AN01363B

Chemometric analysis of integrated FTIR and Raman spectra obtained by non-invasive exfoliative cytology for the screening of oral cancer

Aritri Ghosh, Sreyan Raha, Susmita Dey, Kabita Chatterjee, Amit Roy Chowdhury and Ananya Barui

Analyst, 2019, 144, 1309
DOI: 10.1039/C8AN02092B

Biomedical applications of vibrational spectroscopy: Oral cancer diagnostics

Hugh J. Byrne, Isha Behl, Genecy Calado, Ola Ibrahim, Mary Toner, Sheila Galvin, Claire M. Healy, Stephen Flint and Fiona M. Lyng

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 252, 119470
DOI: 10.1016/j.saa.2021.119470

Raman spectroscopy for detecting gastric and liver cancer cells that entered a tolerant persistence state to survive cisplatin chemotherapy

Anjali Singh, Ishika Gupta, Panchali Saha, Arti Hole, Flevia Anthony, Abhiram Natu, Duane T. Smoot, Hassan Ashktorab, Murali Krishna Chilakapati and Sanjay Gupta

Biochemical and Biophysical Research Communications, 2025, 790, 152891
DOI: 10.1016/j.bbrc.2025.152891

Classification of cytological samples from oral potentially malignant lesions through Raman spectroscopy: A pilot study

Isha Behl, Genecy Calado, Anika Vishwakarma, Damien Traynor, Stephen Flint, Sheila Galvin, Claire M. Healy, Marina Leite Pimentel, Alison Malkin, Hugh J. Byrne and Fiona M. Lyng

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 266, 120437
DOI: 10.1016/j.saa.2021.120437

Raman Spectroscopy Analysis for Optical Diagnosis of Oral Cancer Detection

Ming-Jer Jeng, Mukta Sharma, Lokesh Sharma, Ting-Yu Chao, Shiang-Fu Huang, Liann-Be Chang, Shih-Lin Wu and Lee Chow

JCM, 2019, 8, 1313
DOI: 10.3390/jcm8091313

A New Look into Cancer—A Review on the Contribution of Vibrational Spectroscopy on Early Diagnosis and Surgery Guidance

Adriana P. Mamede, Inês P. Santos, Ana L. M. Batista de Carvalho, Paulo Figueiredo, Maria C. Silva, Mariana V. Tavares, Maria P. M. Marques and Luís A. E. Batista de Carvalho

Cancers, 2021, 13, 5336
DOI: 10.3390/cancers13215336

A multivariate statistical investigation of background subtraction algorithms for Raman spectra of cytology samples recorded on glass slides

L.T. Kerr and B.M. Hennelly

Chemometrics and Intelligent Laboratory Systems, 2016, 158, 61
DOI: 10.1016/j.chemolab.2016.08.012

Optical diagnostics in oral cancer: An update on Raman spectroscopic applications

Aditi Sahu and C. Murali Krishna

Journal of Cancer Research and Therapeutics, 2017, 13, 908
DOI: 10.4103/0973-1482.191032

Serum Raman spectroscopy: Evaluation of tumour load variations in experimental carcinogenesis

Priyanka A. Jadhav, Arti Hole, Arvind Ingle, Rukmini Govekar, Hemanth Noothalapati and C. Murali Krishna

Journal of Biophotonics, 2024, 17
DOI: 10.1002/jbio.202300424

Raman spectroscopy in oral cavity and oropharyngeal cancer: a systematic review

C.I. Faur, A. Falamas, M. Chirila, R.C. Roman, H. Rotaru, M.A. Moldovan, S. Albu, M. Baciut, I. Robu and M. Hedesiu

International Journal of Oral and Maxillofacial Surgery, 2022, 51, 1373
DOI: 10.1016/j.ijom.2022.02.015

Raman spectroscopy and chemometrics: A potential universal method for diagnosing cancer

Nicole M. Ralbovsky and Igor K. Lednev

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 219, 463
DOI: 10.1016/j.saa.2019.04.067

Machine learning algorithm ensembles for early oral cancer risk assessment using Raman cyto-spectroscopy

Dwiteeya Chaudhuri, Aritri Ghosh, Sreyan Raha, Ayushman Chakraborty, Kabita Chatterjee and Ananya Barui

Soft Comput, 2023, 27, 13861
DOI: 10.1007/s00500-023-08995-z

Exploratory Raman Spectroscopic Studies of Canine Oral Tumour Types

Priyanka A. Jadhav, Arti Hole, Panchali Saha, Kshama Pansare, Aishwarya Ghanwat, Poonam Gera, Kiran Bendale, C. Murali Krishna and Pradip Chaudhari

Journal of Biophotonics, 2025, 18
DOI: 10.1002/jbio.202400372

Raman microspectroscopic study for the detection of oral field cancerisation using brush biopsy samples

Isha Behl, Genecy Calado, Anika Vishwakarma, Stephen Flint, Sheila Galvin, Claire M. Healy, Marina Leite Pimentel, Alison Malkin, Hugh J. Byrne and Fiona M. Lyng

Journal of Biophotonics, 2020, 13
DOI: 10.1002/jbio.202000131

Identification of high-risk oral leukoplakia (OLK) using combined Raman spectroscopic analysis of brush biopsy and saliva samples: A proof of concept study

Isha Behl, Genecy Calado, Anika Vishwakarma, Damien Traynor, Stephen Flint, Sheila Galvin, Claire M. Healy, Alison Malkin, Hugh J. Byrne and Fiona M. Lyng

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 330, 125721
DOI: 10.1016/j.saa.2025.125721

Exploration of Raman exfoliated cytology for oral and cervical cancers

Arti Hole, Gunjan Tyagi, Aditi Sahu, Rubina Shaikh and C. Murali Krishna

Vibrational Spectroscopy, 2018, 98, 35
DOI: 10.1016/j.vibspec.2018.07.001

Raman Spectroscopy in Colorectal Cancer Diagnostics: Comparison of PCA-LDA and PLS-DA Models

Wenjing Liu, Zhaotian Sun, Jinyu Chen and Chuanbo Jing

Journal of Spectroscopy, 2016, 2016, 1
DOI: 10.1155/2016/1603609

Raman Spectroscopy: An Exploratory Study to Identify Post-Radiation Cell Survival

Kshama Pansare, Saurav Raj Singh, Venkatavaradhan Chakravarthy, Neha Gupta, Arti Hole, Poonam Gera, Rajiv Sarin and Chilakapati Murali Krishna

Appl Spectrosc, 2020, 74, 553
DOI: 10.1177/0003702820908352

A pilot study for early detection of oral premalignant diseases using oral cytology and Raman micro‐spectroscopy: Assessment of confounding factors

Isha Behl, Genecy Calado, Alison Malkin, Stephen Flint, Sheila Galvin, Claire M. Healy, Marina Leite Pimentel, Hugh J. Byrne and Fiona M. Lyng

Journal of Biophotonics, 2020, 13
DOI: 10.1002/jbio.202000079

Tobacco Consumption Induced Changes in the Healthy Oral Mucosa and its Effect on Differential Diagnosis of Oral Lesions - A Clinical In Vivo Raman Spectroscopic Study

Hemant Krishna, Sidramesh Muttagi, Pranav Ingole, Pankaj Chaturvedi and Shovan Kumar Majumder

J. Anal. Oncol., 2016, 5
DOI: 10.6000/1927-7229.2016.05.03.4

Identification of the Cellular Tipping Point in the Inflammation Model of LPS-Induced RAW264.7 Macrophages Through Raman Spectroscopy and the Dynamical Network Biomarker Theory

Akinori Taketani, Shota Koshiyama, Takayuki Haruki, Shota Yonezawa, Jun Tahara, Moe Yamazaki, Yusuke Oshima, Akinori Wada, Tsutomu Sato, Keiichi Koizumi, Isao Kitajima and Shigeru Saito

Molecules, 2025, 30, 920
DOI: 10.3390/molecules30040920

Label-free Raman spectroscopy: A potential tool for early diagnosis of diabetic keratopathy

Haohao Guan, Chunyan Huang, Dechan Lu, Guannan Chen, Juqiang Lin, Jianzhang Hu, Youwu He and Zufang Huang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 256, 119731
DOI: 10.1016/j.saa.2021.119731

Unique spectral markers discern recurrent Glioblastoma cells from heterogeneous parent population

Ekjot Kaur, Aditi Sahu, Arti R. Hole, Jacinth Rajendra, Rohan Chaubal, Nilesh Gardi, Amit Dutt, Aliasgar Moiyadi, C. Murali Krishna and Shilpee Dutt

Sci Rep, 2016, 6
DOI: 10.1038/srep26538

Raman exfoliative cytology for oral precancer diagnosis

Aditi Sahu, Poonam Gera, Venkatesh Pai, Abhishek Dubey, Gunjan Tyagi, Mandavi Waghmare, Sandeep Pagare, Manoj Mahimkar and C. Murali Krishna

J. Biomed. Opt, 2017, 22, 1
DOI: 10.1117/1.JBO.22.11.115003

Salivary Raman Spectroscopy: Standardization of Sampling Protocols and Stratification of Healthy and Oral Cancer Subjects

Arti Hole, Gunjan Tyagi, Atul Deshmukh, Raviraj Deshpande, Vikram Gota, Pankaj Chaturvedi and C. Murali Krishna

Appl Spectrosc, 2021, 75, 581
DOI: 10.1177/0003702820973260

Raman exfoliative cytology for prognosis prediction in oral cancers: A proof of concept study

Aditi Sahu, Poonam Gera, Akshat Malik, Sudhir Nair, Pankaj Chaturvedi and C. Murali Krishna

Journal of Biophotonics, 2019, 12
DOI: 10.1002/jbio.201800334

Applications of Raman spectroscopy in cancer diagnosis

Gregory W. Auner, S. Kiran Koya, Changhe Huang, Brandy Broadbent, Micaela Trexler, Zachary Auner, Angela Elias, Katlyn Curtin Mehne and Michelle A. Brusatori

Cancer Metastasis Rev, 2018, 37, 691
DOI: 10.1007/s10555-018-9770-9

Novel Quantitative Analysis Using Optical Imaging (VELscope) and Spectroscopy (Raman) Techniques for Oral Cancer Detection

Ming-Jer Jeng, Mukta Sharma, Lokesh Sharma, Shiang-Fu Huang, Liann-Be Chang, Shih-Lin Wu and Lee Chow

Cancers, 2020, 12, 3364
DOI: 10.3390/cancers12113364

Hierarchical deep convolutional neural networks combine spectral and spatial information for highly accurate Raman‐microscopy‐based cytopathology

Sascha D. Krauß, Raphael Roy, Hesham K. Yosef, Tatjana Lechtonen, Samir F. El‐Mashtoly, Klaus Gerwert and Axel Mosig

Journal of Biophotonics, 2018, 11
DOI: 10.1002/jbio.201800022

Developing an Algorithm for Discriminating Oral Cancerous and Normal Tissues Using Raman Spectroscopy

Mukta Sharma, Ming-Jer Jeng, Chi-Kuang Young, Shiang-Fu Huang and Liann-Be Chang

JPM, 2021, 11, 1165
DOI: 10.3390/jpm11111165

Identification of morphological and biochemical changes in keratin‐8/18 knock‐down cells using Raman spectroscopy

S. P. Singh, Hunain Alam, Crismita Dmello, Hitesh Mamgain, Milind M. Vaidya, Ramachandra Rao Dasari and C. Murali Krishna

Journal of Biophotonics, 2017, 10, 1377
DOI: 10.1002/jbio.201600249