Issue 2, 2021

Catalytic challenges and strategies for the carbonylation of σ-bonds

Abstract

The carbene character of carbon monoxide offers the possibility to utilize this C1-building block for the carbonylation of a variety of organic substrates by insertion of CO into σ-bonds. Although presenting an ideal atom economy this route requires the design and utilization of reactive catalysts able to activate strong C–O, C–N, and C–H bonds in the presence of carbon monoxide. This perspective article addresses, in the context of sustainable chemistry, the challenges and strategies facing the catalytic carbonylation of σ-bonds and presents the key advances in the field over the last few decades, for the carbonylation polar and apolar substrates, such as the conversion of alcohols to formates and esters and the carbonylation of amines to amides.

Graphical abstract: Catalytic challenges and strategies for the carbonylation of σ-bonds

Article information

Article type
Perspective
Submitted
09 ጁላይ 2020
Accepted
04 ጃንዩ 2021
First published
04 ጃንዩ 2021

Green Chem., 2021,23, 723-739

Catalytic challenges and strategies for the carbonylation of σ-bonds

T. Nasr Allah, L. Ponsard, E. Nicolas and T. Cantat, Green Chem., 2021, 23, 723 DOI: 10.1039/D0GC02343D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements