Decarboxylative cyclization of o-chlorobenzoic acids with C,C-palladacycles formed by an aminopalladation/dealkylation strategy to access dibenzo[a,c]carbazoles

Abstract

Herein a novel palladium-catalyzed tandem decarboxylative biscyclization of o-alkynylanilines with o-chlorobenzoic acids has been reported, which provides an efficient approach for the assembly of dibenzo[a,c]carbazoles. This protocol employs an intramolecular aminopalladation/dealkylation strategy to form C,C-palladacycles, which allow the construction of one C–N bond and two C–C bonds by reacting with o-chlorobenzoic acids. The method features a broad substrate scope and excellent functional group compatibility.