Issue 13, 2022

Glass-patternable notch-shaped microwave architecture for on-chip spin detection in biological samples

Abstract

We report a notch-shaped coplanar microwave waveguide antenna on a glass plate designed for on-chip detection of optically detected magnetic resonance (ODMR) of fluorescent nanodiamonds (NDs). A lithographically patterned thin wire at the center of the notch area in the coplanar waveguide realizes a millimeter-scale ODMR detection area (1.5 × 2.0 mm2) and gigahertz-broadband characteristics with low reflection (∼8%). The ODMR signal intensity in the detection area is quantitatively predictable by numerical simulation. Using this chip device, we demonstrate a uniform ODMR signal intensity over the detection area for cells, tissue, and worms. The present demonstration of a chip-based microwave architecture will enable scalable chip integration of ODMR-based quantum sensing technology into various bioassay platforms.

Graphical abstract: Glass-patternable notch-shaped microwave architecture for on-chip spin detection in biological samples

Supplementary files

Article information

Article type
Paper
Submitted
03 ፌብሩ 2022
Accepted
26 ኤፕሪ 2022
First published
01 ሜይ 2022

Lab Chip, 2022,22, 2519-2530

Author version available

Glass-patternable notch-shaped microwave architecture for on-chip spin detection in biological samples

K. Oshimi, Y. Nishimura, T. Matsubara, M. Tanaka, E. Shikoh, L. Zhao, Y. Zou, N. Komatsu, Y. Ikado, Y. Takezawa, E. Kage-Nakadai, Y. Izutsu, K. Yoshizato, S. Morita, M. Tokunaga, H. Yukawa, Y. Baba, Y. Teki and M. Fujiwara, Lab Chip, 2022, 22, 2519 DOI: 10.1039/D2LC00112H

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