Issue 9, 2022

Photoredox catalyzed C–H trifluoroethylamination of heteroarenes

Abstract

The first C–H trifluoroethylamination of heteroarenes with previously unknown N-trifluoroethyl hydroxylamine reagents was achieved under photoredox catalyzed conditions. In the presence of an iridium(III) photoredox catalyst, a variety of heteroarenes, such as indoles, benzofurans, and benzothiophenes, were smoothly converted to the trifluoroethylaminated products in moderate to high yields and with excellent regioselectivity.

Graphical abstract: Photoredox catalyzed C–H trifluoroethylamination of heteroarenes

Supplementary files

Article information

Article type
Communication
Submitted
29 ኖቬም 2021
Accepted
20 ዲሴም 2021
First published
05 ጃንዩ 2022

Chem. Commun., 2022,58, 1346-1349

Photoredox catalyzed C–H trifluoroethylamination of heteroarenes

J. Wang, S. Liu, Y. Huang, X. Xu and F. Qing, Chem. Commun., 2022, 58, 1346 DOI: 10.1039/D1CC06688A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements