Issue 8, 2021

Copper-catalyzed redox-neutral regioselective chlorosulfonylation of vinylarenes

Abstract

A copper-catalyzed redox-neutral, regioselective aromatic alkene chlorosulfonylation reaction has been developed. This protocol features simple procedure, easily accessible materials and good functional group tolerance. Moreover, it could be amplified to a gram scale and smoothly applied to the late-stage modification of bioactive molecule derivatives.

Graphical abstract: Copper-catalyzed redox-neutral regioselective chlorosulfonylation of vinylarenes

Supplementary files

Article information

Article type
Communication
Submitted
12 ሜይ 2021
Accepted
10 ጁን 2021
First published
16 ጁን 2021

React. Chem. Eng., 2021,6, 1376-1380

Copper-catalyzed redox-neutral regioselective chlorosulfonylation of vinylarenes

L. Liu and C. Wang, React. Chem. Eng., 2021, 6, 1376 DOI: 10.1039/D1RE00188D

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