Issue 18, 2021

Cross-dehydrogenative coupling: a sustainable reaction for C–C bond formations

Abstract

We are entering an era that emphasizes greenness and sustainability. Based on such a philosophy, it is critical to uncover novel and original sustainable reaction modes for future green chemical syntheses. The cross-dehydrogenative coupling (CDC) reaction has thus been widely developed as one of the most sustainable and efficient synthesis strategies for constructing C–C bonds. This review summarizes the development of this field over the past 20 years, with a discussion on future trends and directions: from the original reaction model at the beginning and its development in the first decade, to extensive research in the second decade. The latest development sees the emergence of alternative forms of energy inputs (photoredox, mechano, microwave, electrochemical, continuous-flow and solar quantum dots) to facilitate CDC reactions, gradually replacing the classical form of thermal energy, which will inspire broader applications and innovations in the future.

Graphical abstract: Cross-dehydrogenative coupling: a sustainable reaction for C–C bond formations

Associated articles

Article information

Article type
Tutorial Review
Submitted
26 ሜይ 2021
Accepted
23 ጁላይ 2021
First published
23 ጁላይ 2021

Green Chem., 2021,23, 6789-6862

Cross-dehydrogenative coupling: a sustainable reaction for C–C bond formations

T. Tian, Z. Li and C. Li, Green Chem., 2021, 23, 6789 DOI: 10.1039/D1GC01871J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements