Issue 87, 2017

Programmable fusion of liposomes mediated by lipidated PNA

Abstract

We recently reported a DNA-programmed fusion cascade enabling the use of liposomes as nanoreactors for compartmentalized chemical reactions. This communication reports an alternative and robust strategy based on lipidated peptide nucleic acids (LiPs). LiPs enabled fusion of liposomes with remarkable 31% efficiency at 50 °C with low leakage (5%).

Graphical abstract: Programmable fusion of liposomes mediated by lipidated PNA

Supplementary files

Article information

Article type
Communication
Submitted
03 ኦገስ 2017
Accepted
11 ኦክቶ 2017
First published
11 ኦክቶ 2017

Chem. Commun., 2017,53, 11921-11924

Programmable fusion of liposomes mediated by lipidated PNA

A. Rabe, P. M. G. Löffler, O. Ries and S. Vogel, Chem. Commun., 2017, 53, 11921 DOI: 10.1039/C7CC06058K

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