Metal-free oxidative phosphinylation of aryl alkynes to β-ketophosphine oxides via visible-light photoredox catalysis

Abstract

A method for photocatalytic oxidative coupling of diaryl phosphine oxide and arylacetylene under mild conditions was developed. Rhodamine B, an inexpensive and commercially available organic dye, was used as the photocatalyst. This protocol realizes a regioselective 1,2-difunctionalization of arylacetylenes and provides a metal-free access toward a series of β-ketophosphine oxides.