Issue 11, 2015
From the journal:

RSC Advances

The aqueous medium-dimethylsulfoxide conundrum in biological studies

Saeedeh Negin,ab   Michael R. Gokel,a   Mohit B. Patel,bc   Sergey L. Sedinkin,ab   David C. Osborna  and  George W. Gokel*abc  

* Corresponding authors

a Center for Nanoscience, University of Missouri-St. Louis, St. Louis, Missouri, USA
E-mail: gokelg@umsl.edu
Fax: +1-314-516-5342
Tel: +1-314-516-5321

b Dept. of Chemistry, University of Missouri-St. Louis, St. Louis, Missouri, USA

c Department of Biology, University of Missouri-St. Louis, St. Louis, Missouri, USA

Abstract

A series of straight and branched chain pyrogallol[4]arenes was studied and found to be essentially nontoxic to two strains of E. coli. An apparent enhancement of potency observed for kanamycin against E. coli was found to be due to the presence of DMSO in the growth media. Quantitative studies are presented that assay the effect of DMSO concentration on the apparent potency of kanamycin against E. coli.

Graphical abstract: The aqueous medium-dimethylsulfoxide conundrum in biological studies

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C4RA15217D
Article type
Paper
Submitted
25 ኖቬም 2014
Accepted
15 ዲሴም 2014
First published
15 ዲሴም 2014

RSC Adv., 2015,5, 8088-8093

Permissions

Request permissions

The aqueous medium-dimethylsulfoxide conundrum in biological studies

S. Negin, M. R. Gokel, M. B. Patel, S. L. Sedinkin, D. C. Osborn and G. W. Gokel, RSC Adv., 2015, 5, 8088 DOI: 10.1039/C4RA15217D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements