Issue 9, 2015

Synthesis of imidazo[1,2-a]pyridines: a decade update

Abstract

Imidazopyridine is one of the important fused bicyclic 5–6 heterocycles and it is recognized as a “drug prejudice” scaffold due to its wide range of applications in medicinal chemistry. This moiety is also useful in material science because of its structural character. Synthesis of this moiety from the easily available chemicals is desirable due to its tremendous use in the various branches of chemistry. Here we report a review on the synthesis of this scaffold employing different strategies such as condensation, multicomponent reactions, oxidative coupling, tandem reactions, aminooxygenation, and hydroamination reactions.

Graphical abstract: Synthesis of imidazo[1,2-a]pyridines: a decade update

Article information

Article type
Feature Article
Submitted
28 ኦክቶ 2014
Accepted
06 ኖቬም 2014
First published
06 ኖቬም 2014

Chem. Commun., 2015,51, 1555-1575

Synthesis of imidazo[1,2-a]pyridines: a decade update

A. K. Bagdi, S. Santra, K. Monir and A. Hajra, Chem. Commun., 2015, 51, 1555 DOI: 10.1039/C4CC08495K

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