Issue 18, 2011
From the journal:

Chemical Communications

Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study†

Nanda Gopal Sahoo,a   Hongqian Bao,a   Yongzheng Pan,a   Mintu Pal,a   Mitali Kakran,a   Henry Kuo Feng Cheng,a   Lin Li*a  and  Lay Poh Tanb  

* Corresponding authors

a School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore
E-mail: mlli@ntu.edu.sg

b School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore

Abstract

Carbon nanomaterials such as multiwalled carbon nanotubes (MWCNTs) and graphene oxide (GO) have been functionalized by highly hydrophilic and biocompatible poly(vinyl alcohol) (PVA) for loading and delivery of an anticancer drug, camptothecin (CPT). For the first time, CPT was loaded onto MWCNT–PVA and GO–PVA through π–π interactions and its capability to kill human breast and skin cancer cells was investigated.

Graphical abstract: Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study

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Article information

DOI
https://doi.org/10.1039/C1CC00075F
Article type
Communication
Submitted
05 ጃንዩ 2011
Accepted
14 ማርች 2011
First published
30 ማርች 2011

Chem. Commun., 2011,47, 5235-5237

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Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study

N. G. Sahoo, H. Bao, Y. Pan, M. Pal, M. Kakran, H. K. F. Cheng, L. Li and L. P. Tan, Chem. Commun., 2011, 47, 5235 DOI: 10.1039/C1CC00075F

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