Ethyl 2-benzyloxy-3,3-difluoropropenoate 3, prepared from the readily obtainable ethyl trifluoropyruvate, reacts with a variety of nucleophiles to give β-fluoro-α-keto acid derivatives in high yield.
G. Shi and Z. Cao, J. Chem. Soc., Chem. Commun., 1995, 1969 DOI: 10.1039/C39950001969
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