We report an efficient TCCA/PhSH-mediated regioselective hydroethoxylation and hydromethoxylation of allenamides via a radical process to create a workable route to γ-oxygenated enamides.
Hexafluoroisopropanol mediated di-π-functionalization of allenamides with 4-hydroxycoumarin was developed. This strategy features a general cascade C–C and C–O bond formation process for accessing novel pyranocoumarins.
Synthesis of iodine-substituted allylic pyrazoles through NIS-mediated regioselective addition of allenamides with pyrazoles.
A photocatalytic strategy has been developed for the selective synthesis of (E)-β-aminovinyl sulfones and (E)-β-amidovinyl sulfones through the utilization of allenamides and sodium sulfinates.
Efficient access to dibenzo[1,4]oxazocines via palladium-catalysed arylalkylation of allenamides has been developed.