A membrane-dependent methyltransferase acts as a molecular switch, diverting a dihydroxybenzyl alcohol precursor toward dedicated para-quinone methide biosynthesis and oligomerization.
The defluoroborylation of fluoroarenes by chromium-catalyzed cleavage of unactivated C–F bonds is described.
In recent years, ortho-quinone methides have emerged as indispensable reactive species for enhancing synthetic efficiency in accessing various bioactive natural products.
A new classification system is used to summarise mechanisms of photochemical generation of quinone methides. Recent mechanistic studies that used ultrafast techniques are compared with old mechanistic studies that used conventional techniques.
Decarbonylative borylation of aryl anhydrides by rhodium catalysis has been reported. A base-free system with Rh(PPh3)3Cl as a catalyst allows efficient synthesis of arylboronate esters from readily available aryl anhydrides. The reaction involves cleavage of C(O)–O bonds and formation of C–B bonds.