Three phenoxazine-embedded hexaphyrins were synthesized by replacement of phenothiazine with phenoxazine which induces a complete flip of the heterocyclic unit which profoundly modulates the macrocyclic architecture and electronic properties.
New donor-carbazole-acceptor derivatives can exhibit fluorescence in the blue–orange spectral range. The observed emission suggests the involvement of through bond and through space charge transfers.
The polarity dependent torsional motion plays a significant role in the excited state relaxation pathways of multibranched donor–acceptor derivatives.
A series of N-sulfonylphenoxazines were synthesised and tested for CaV2.2 and CaV3.2 ion channel inhibition. Compounds with low micromolar activity for CaV2.2 had good plasma stability and liver microsomal stability, and favourable CNS MPO scores.
A new class of phenoxazine-based luminescent liquid crystal molecules exhibiting room temperature liquid crystallinity, ambipolar charge carrier mobility which also can be used for bioimaging were synthesized.