A variety of arsa-Buchwald ligands, which are arsenic analogues of Buchwald ligands, were synthesized. The optimal arsa-Buchwald ligand gave an excellent catalytic activity for the Suzuki–Miyaura coupling reaction of sterically hindered substrates.
This article presents a comprehensive analysis of the progress in palladium-catalyzed coupling reactions, with an emphasis on how ligand characteristics affect the chemoselectivity of aryl (pseudo)halides.
Two novel SNS-donor palladium(II) complexes of benzoxazole and benzothiazole derivatives display excellent antiproliferative activity against all tested cancer cell lines, particularly human colon cancer HCT-116 cells.
This study highlights the advantages of arsine ligands over phosphines in Pd-catalyzed C–H difunctionalization. Analysis of 36 arsines shows higher steric accessibility and oxidative stability, enabling new catalyst designs beyond phosphine limits.
4,4′-Bipyridinium-based ditopic ligands assemble with Pd(II) centers generating constitutionally dynamic systems in which concentration is a suitable stimulus to influence the speciation between mononuclear [PdL]5+ and dinuclear [Pd2L2]10+ species.