Recent synthetic journey on pyrrole-fused compounds

Chandana Pramanik, Paritosh Barik, Sk Asraf Ali, Dipti Sovamayee Nayak, Mohammed Ikbal, Arabinda Mandal, Rathin Jana, Soumen Giri and Shubhankar Samanta

New J. Chem., 2023, 47, 6476
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C(3)-Aryl isoindolinones: a PTSA-mediated access and improved synthesis of (±)-nuevamine

H. Surya Prakash Rao and Prabhakaran J

New J. Chem., 2023, 47, 19283
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Photocatalytic hydroalkylation of 3-methyleneisoindolin-1-ones with unactivated alkyl iodides

Abhishek Kumar, Shrutheka G. S. and Veera Reddy Yatham

Chem. Commun., 2025, 61, 6340
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Tetrabutylammonium decatungstate-catalyzed hydroalkylation/alkoxylation of 3-methyleneisoindolin-1-ones with alcohols/ethers through hydrogen atom transfer process

Han Fu, Feixia Wang, Ziyan Wu, Xiaoyu Xie, Yicheng Zhang, Jie Liu and Lei Wang

RSC Adv., 2025, 15, 30285
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Atroposelective [4+1] annulation for the synthesis of isotopic isoindolinones bearing both central and axial chirality

Jun Gu, Li-Hong Zhang, Hong-Feng Zhuang and Ying He

Chem. Sci., 2025, 16, 5735
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Synthesis of fungicidal morpholines and isochromenopyridinones via acid-catalyzed intramolecular reactions of isoindolinones

Xiaoyu Liu, Yaru Sun, Shuang Hong, Xia Ji, Wei Gao, Haolin Yuan, Yue Zhang, Bin Lei, Liangfu Tang and Zhijin Fan

Org. Biomol. Chem., 2024, 22, 120
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Electroselective C(sp3)–H deuteration of isoindolinones

Qiansong Gao, Lianyou Zheng, Shulin Ning, Lingling Shi, Cheng Wu, Mian Liu and Jinbao Xiang

Org. Chem. Front., 2023, 10, 6212
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Metal-Free Cascade Synthesis of 1,2,4-Thiadiazoles from β-Ketothioamides and Alkyl/Aryl Cyanides under TBN Enabling Conditions at Room Temperature

Saurabh Singh, Gaurav Shukla, Subhasish Ray and Maya Shankar Singh

Synthesis, 2023, 55, 1893
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Synthesis of Anti‐Alzheimer Molecules: Bridging Chemical Approaches to Pharmaceuticals

Hasan Abbas, Noor Fatima, Shehla Khalid, Matloob Ahmad, Nasir Rasool, Ayesha Malik and Muhammad Imran

ChemistrySelect, 2025, 10
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On Route to Diverse Nitrogen‐Bridged Polyhetero‐cycles with an N(acyl), N(aryl)‐acetal Core

Valerio Morlacci, Tonino Caruso, Marco Chiarini, Vincenzo Marsicano, Antonio Arcadi and Laura Palombi

ChemistrySelect, 2023, 8
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Enantioselective Synthesis of Isoindolones via Palladium – Catalyzed Intramolecular Heck‐Mizoroki Reactions of Endocyclic Enamides Using N,N‐Ligands

Carson Wiethan, Ingredy B. Braga, Vitor H. Menezes da Silva, João M. Batista and Carlos Roque D. Correia

ChemCatChem, 2023, 15
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Discovery of New Immunomodulatory Anticancer Thalidomide Analogs: Design, Synthesis, Biological Evaluation and In Silico Studies

Abdallah E. Abdallah, Ibrahim H. Eissa, Ahmed B. M. Mehany, Ismail Celik, Helmy Sakr, K. H. Metwaly, Khaled El‐Adl and Mohamed Ayman El‐Zahabi

Chemistry & Biodiversity, 2025, 22
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Synthesis of 3,3-disubstituted allyl isoindolinones via Pd-catalyzed decarboxylative allylic alkylation

Mario Alvarado, Marisa Loo, Hanna Adler, Caroline Arnall, Katharine Amsden, Gisela Martinez and Raul Navarro

Tetrahedron Letters, 2024, 148, 155242
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Heterobenzylic C(sp3)─H Acylation of Isoindolinones via Photoinduced Intermolecular Hydrogen Atom Transfer Strategy

Karthick Muthuvel, Chandrasekaran Sivaraj and Thirumanavelan Gandhi

Synlett, 2025, 36, 3373
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Visible-light-driven photocatalyst-free multicomponent reaction for synthesis of C3-alkylated isoindolinones

Lifang Qi, Zhen Yao, Rong Huang, Yuanyuan Wang, Xiongwei Liu, Ying Zhou and Lijin Xu

Green Synthesis and Catalysis, 2025
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Photoinduced Charge-Transfer Complex Enables ortho-Fluorobenzamide C–F Bond Activation in Isoindolinone Synthesis

He Sheng, Xin Zhang and Xiang-Yu Chen

Synthesis, 2026, 58, 679
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Synthesis of Multifused Pyrrolo[1,2-a]quinoline Systems by Tandem Aza-Michael–Aldol Reactions and Their Application to Molecular Sensing Studies

Anirban Bera, Sk Abulkalam Azad, Prasanta Patra, Nayim Sepay, Rathin Jana, Tapas Das, Amit Saha and Shubhankar Samanta

J. Org. Chem., 2023, 88, 5622
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Carbene-Catalyzed Tandem Imine Umpolung–Intramolecular Aza-Conjugate Addition–Oxidation to Access N-Substituted Isoindolinones

Jakkula Ramarao, Purna Chandra Behera, Manyam Subbi Reddy and Surisetti Suresh

J. Org. Chem., 2024, 89, 414
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Phthalimidine Synthesis via Iridium-Catalyzed Reductive Lactamization

Jingyu Zhang, Yang Chen, Jiaxi Xu and Zhanhui Yang

J. Org. Chem., 2025, 90, 691
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Rh(III)-Catalyzed Aminoalkylation of Alkenes with Diazo Compounds toward Functionalized Isoindolinones

Yuying Liu, Zhanwei Fu, Chao Yang, Mupeng Luo, Shurong Ban and Shouguo Wang

Chinese Journal of Organic Chemistry, 2024, 44, 3505
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One-Pot Synthesis of Isoindolinones Mediated by LiN(SiMe3)2/CsF

Ruyuan Ma, Yuanyun Gu, Yan-En Wang, Rongbi Fei, Dan Xiong and Jianyou Mao

Org. Lett., 2026, 28, 2547
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Facile Synthesis of Isoindolinones via Radical-Mediated Intramolecular Coupling of Two C–H Bonds

Shuxiong Han, Shuo He, Zhibin Huang, Yingsheng Zhao and Gong Chen

Synlett, 2023, 34, 1457
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A Unified Approach to Lactonization/Lactamization by Leveraging Tether-Tunable Distonic Radical Anions

Congyin Wei, Denghu Chang, Na Feng, Ziye Zhan and Lei Shi

Org. Lett., 2025, 27, 2582
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Electrochemical Aerobic Oxidation and Cyclization of 2-Alkylbenzamides toward 3-Hydroxyisoindolinones

Jee Eun Hong, Haein Jeon, Jae-Hwan Kwak, Seokwoo Lee and Yohan Park

J. Org. Chem., 2025, 90, 8152
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Heterogeneous photocatalytic aldehyde alkylative amination for multicomponent synthesis of α-branched amines

Wei Ou, Qingzhu Xu, Qiyuan Wang, Ying Tao, Jie Wang, Zhenyuan Teng, Fuhua Li, Jie Ding, Wei Liu, Hao Hou, Akira Yamakata, Teruhisa Ohno, Bin Liu and Chenliang Su

National Science Review, 2026, 13
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Palladium Nanoparticles on Graphite Oxide (Pd@GO) as an Efficient Catalyst for the Synthesis of Secondary Amines and Aminoisoindolinones

Lenida Kyndiah, Rona Moni Bora, Priyanka Borah and Amarta Kumar Pal

Applied Organom Chemis, 2025, 39
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A Detailed Review on C‐Fused Furan/3,4‐Fused Furan Analog and its Potential Applications

Susanta Kumar Manna, Soumen Giri, Sampa Mondal, Rabindra Nath Sana, Aroop Kumar Samal and Arabinda Mandal

ChemistrySelect, 2023, 8
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Xantphos–Cu‐Decorated Covalent Organic Frameworks for C─H Arylation through Sensitized Electron Transfer

Akhtar Alam, Monojit Roy, Shyamali Maji, Avanti Chakraborty, Vikramjeet Singh, Amit Kumar, Sukanta Mondal, Abhik Banerjee, Kamalakannan Kailasam, Debashis Adhikari and Pradip Pachfule

Advanced Materials, 2025, 37
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